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Microdosimetry Extension

The current version of the TOPAS microdosimetry extension includes scorers to retrieve microdosimetric spectra from primary and secondary particles. The extension is available on the TOPAS GitHub page. The included examples show how to score RBE with a biological weighting function or with the microdosimetric kinetic model (MKM). Two geometries of tissue equivalent proportional counter (TEPC) are provided. The extension was validated in the following reference.

Zhu, H., Chen, Y., Sung, W., McNamara, A. L., Tran, L. T., Burigo, L. N., et al. (2019). The microdosimetric extension in TOPAS: development and comparison with published data. Physics in Medicine and Biology, 64(14)-145004.